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Studied Benefits Increased GH and IGF-1 secretion Phase I/II clinical studies have shown that CJC-1295 DAC increases plasma GH levels by 2- to 10-fold and IGF-1 levels by 1.5- to 3-fold compared to baseline values, with a sustained effect lasting 6 to 14 days after a single injection

The location of the Q178L mutation is shown with two nearby protomers highlighted

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Moreover a null mutant in GSH1 is embryo lethal 69